FAQ

Frequent Questions

  • The expected success rate from IVF cycle is in the range of 30 to 35 %.
  • The success rate of IVF cycle depends on the patient profile, standard of equipments and Quality Protocols.
  • Success rate of IVF cycle is calculated with the following formula (Number of Clinical Pregnancy)/(Number of Embryo Transfer cycles done).
  • If pregnancy is positive 14 days after Embryo Transfer, a chemical named B-HCG is present in the blood, which doubles in 48 hours. This is called Chemical pregnancy. 2 weeks after this Sonography is done to detect the activity of heart of fetus (baby in uterus). This is called Clinical Pregnancy.
  • The most current data available in the United States is a 2009 summary complied by the Society for Reproductive Medicine (SART) which reports the average national IVF success rates per age group using non-donor eggs.(Ref: 2009 Clinic Summary Report". Society for Reproductive Medicine)
  • The cost of IVF treatment in India is less than a fifth of that in the U.S.
  • At Morpheus, we have a unique "Double Your Chances" offer, a clinically result oriented and cost effective treatment plan.
  • Double Your Chances treatment plan improves the chances of pregnancy. This is a clinically result oriented plan wherein the couple gets the second cycle free of procedural cost if the first cycle does not lead to clinical pregnancy
  • Team Morpheus collectively represents over 500+ years of practicing expertise in Managing Infertility.
  • Our team of internationally trained and experienced Fertility Specialists, Embryologists, Gynecologists, Andrologists, Holistic Medicine Experts, Counselors, and other skilled clinical staff guide the couples facing difficulties in conceiving, and provide customized solutions to help them achieve healthy parenthood. Morpheus fertility centers are advanced centers for infertility evaluation and assisted reproductive services in the country "WHERE PATIENTS COME FIRST". We understand the sensitive emotions involved in the fertility treatment and provide comprehensive treatment to the couples in a relaxed, caring and supportive environment. We also ensure complete privacy during and after the treatment.
  • Our IVF laboratories adhere to international protocols for handling eggs and sperms.
  • The quality systems ensure that the eggs and sperms are exposed to the most optimal environment. We continuously monitor laboratory parameters to prevent unacceptable incidents and outcomes. Our Embryologists do Quality Checks to ensure the optimum environment for embryo growth in-vitro
  • State-of-the-art equipments and latest techniques like IMSI, Zona Birefringence and Laser hatching which have proved to be a boon to couples in difficult cases.
    Intracytoplasmic Morphologically Selected Sperm Injection (IMSI):
  • IMSI is a highly advanced technique where sperms are magnified to approximately 7200 times to allow selection of better quality sperms for ICSI. This technique offered by Morpheus is a major advantage for the couple with bad morphology (abnormal structure) of sperms. It helps to select the sperms with best shape and size for injecting into the egg.
    Laser Assisted Hatching (LAH):
  • LAH is an advanced technique used when the zona pellucida or the covering of the eggs are thicker than usual. The excessive thickening is believed my many scientists to result in lower chances of implantation which lowers the chances of pregnancy. With the help of a laser, the zona is thinned out at one place, to ease hatching of the embryo, hence improving implantation and pregnancy rates.
    Zona Birefringence:
  • This advanced optical system assists in assessing the quality of the oocyte in a dimension that is not possible with conventional microscopy. Using this technology selection of better oocytes for fertilization is possible, resulting in good quality embryos.
World Health Organization (WHO) definition of infertility is failure to conceive following twelve months of unprotected intercourse in absence of any known pathology.
Global estimates of infertility range between 8-12% of couples with women of child bearing age, affecting between 50 - 80 million people.
Infertility is due to female problem in 30% of the cases and male problem in 30% of the cases. Problems common to both partners are diagnosed in 15-30% of infertile couples. Unexplained infertility is when cause of infertility is not found and is seen in 10-15 % of couples.

Female factors are:
Ovulatory disorders and damaged fallopian tubes are the most common causes of female infertility Other common causes are
  • Endometriosis
  • Tuberculosis
  • Uterine abnormality
  • Endocrine abnormality like Hyperprolactinemia
Male factors are:
  • Sperm production disorders affecting the quality and/or the quantity of sperm
  • Anatomical obstructions
  • Immunological or endocrine problems and failure of the testes to respond to the hormonal stimulation triggering sperm production
  • Inadequate spermatogenesis (sperm production) or sperm defects
  • Immunological factors
A properly timed sexual intercourse substantially increases the possibility of a spontaneous pregnancy. This means that sexual intercourse, or coitus, have to be timed around the time of ovulation. To detect the approximate time of ovulation a temperature curve of several menstrual cycles can be made. The woman takes her body temperature each morning before getting out of bed, starting on the first day of the menstruation until the start of a new period. The body temperature rises around 0.5 degree Celsius after the ovulation. This is mostly about 14 days after the first day of the period and when no pregnancy occur the temperature drops to normal again; with pregnancy the temperature stays high. However these methods are not so accurate.

One can also use urine or saliva tests to detect the ovulation. The time of ovulation can sometimes vary by few days each month, even in a regular menstrual cycle. If the circumstances are favourable then sperms can survive inside the woman for a few days. On the other hand, sperm quality can decrease with high and frequent sexual activity. Therefore it is best to have intercourse 3-4 days before the expected ovulation and every other day until 2-3 days after the expected ovulation. There is no need to increase the frequency of intercourse. When tests are used to detect ovulation it is advised to have sexual intercourse on the day of a positive test.
No. The incidence of infertility in men and women is almost equal. Infertility is due to problem in female in approximately 30%of the cases and problem in male in approximately 30% of the cases. Problems common to both partners are diagnosed in 15-30% of infertile couples. In spite of thorough medical investigations, the causes of the fertility problem remain unexplained in up to 5-10% of infertile couples.
It is recommended that you consult your Gynaecologist, who will try to find out the cause of infertility by advising some investigations to you and your husband. The cause for your infertility can be determined only after you undergo tests to find out if your husband's sperm count is normal, if your fallopian tubes and uterus are normal, and if you are producing good sufficient eggs. It is only after undergoing these tests will your doctor will be able to diagnose the cause of infertility. Based on the diagnosis, Doctor will recommend the best possible solution.
The options offered to couples depend on the cause of infertility diagnosed. The vast majority of female patients are successfully treated with the administration of drugs such as clomiphene citrate, or gonadotropins (FSH). These drugs are called ovulation induction drugs. Surgical repair of Fallopian tubes, removal of adhesions, endometriosis is one of treatment options.

IUI is offered to couple where woman has patent Fallopian tubes and minor issues in sperm concentration and/or ovulation. Women with damaged tubes which are beyond surgical repair, endometriosis or unexplained infertility can be offered IVF or ICSI.

The treatment options for male infertility include administration of drugs, surgery and Intra Cytoplasmic Sperm Injection (ICSI). Assisted Reproductive Technologies (ART) includes a whole gamut of treatment options designed to overcome barriers to natural fertilization such as IVF, ICSI, IMSI. Those women having repeated implantation failure benefit from Laser Hatching.
IUI refers to Intra Uterine Insemination, in which concentrated and washed semen is placed inside the uterus (womb) of the woman. Patent Fallopian Tubes of the woman is the prerequisite for successful IUI. Thus only couple in which the woman has patent fallopian tubes benefit from IUI.

IUI is done around the time of ovulation (release of egg from ovary) to maximise the chances of pregnancy.

IUI is offered to couple having one or more of the following medical conditions:

Husband has
  • Decreased sperm count
  • Decreased sperm motility
  • Difficulty in ejaculation
  • Disorders of Penis
Wife has
  • Anovulatory cycles (to ensure sperm availability during ovulation induction)
  • Disorder of Cervix or Cervical mucous
  • Unexplained infertility
  • Sperm antibodies
In IVF the egg and sperms from the couple are allowed to fuse in a glass dish (In Vitro) and hence the word In Vitro Fertilization. The sperms are layered over the eggs retrieved from the woman and the process of fertilization occurs naturally under optimal conditions inside an incubator.

IVF is offered to couple where there is no qualitative or quantitative defect in sperms and wife having one or more of the following medical conditions:
  • Multiple failed IUI
  • Blocked Fallopian Tubes
  • Pelvic Inflammatory disease (PID) in past
  • Endometriosis (mild)
  • PCOS (Polycystic Ovarian Syndrome)
The steps involved in IVF are:
  1. Controlled ovarian stimulation with hormones for development of multiple eggs
  2. Ovum Pickup under short anaesthesia
  3. Layering of the eggs by washed sperms in petri dish for natural fertilization
  4. Culture till embryo stage in incubator
  5. Transfer of 2-3 best quality embryos inside the uterus (womb)
  6. Detection of pregnancy 14 days after embryo transfer
ICSI is an advanced fertility technique, performed by an Embryologist under a powerful microscope with magnification up to 400 times.

Here, a single egg of the woman is injected with a single sperm of the man. The fertilization rates of ICSI are better than IVF as it bypasses the possible barriers that may prevent the natural fertilization process. This procedure is highly advantageous in qualitative and quantitative defect of sperm/egg.

ICSI is advised to couples having the following medical conditions:
Husband has
  • Low sperm count (Oligospermia)
  • No sperm (Azoospermia)*
  • Low motility of sperms (Asthenozoospermia)
  • Bad morphology (Teratozoospermia)
*In cases where there are no sperms in the semen (Azoospermia), sperms can be retrieved surgically from the testes or male ducts with procedures such as PESA, TESA or TESE.
Wife has
  • Endometriosis (moderate to severe)
  • Poor Ovarian Reserve
  • Premature Menopause (Premature Ovarian Failure) (ICSI with donor eggs)
  • Unexplained Infertility
The steps involved in ICSI are:
  1. Controlled ovarian stimulation with hormones for development of multiple eggs
  2. Ovum Pickup under short anaesthesia, a simple 20 minute procedure
  3. Injecting a single good quality egg with a single good quality sperm by micromanipulator
  4. Culture till embryo stage in incubator
  5. Transfer of 2-3 best quality embryos inside the uterus (womb)
  6. Detection of pregnancy 14 days after embryo transfer
IMSI is a highly advanced technique where sperms are magnified to approximately 7200 times to allow selection of better quality sperms for ICSI. This technique offered by Morpheus is a major advantage for the couple with bad morphology (abnormal structure) of sperms. It helps to select the sperms with best shape and size for injecting into the egg.
LAH is an advanced technique used when the Zona Pellucida or the covering of the Embryo are thicker than usual. The excessive thickening is believed my many scientists to result in lower chances of implantation which lowers the chances of pregnancy. With the help of a laser, the zona is thinned out at one place, to ease hatching of the embryo, hence improving implantation and pregnancy rates.
A correct diagnosis accomplished by investigations and consultation with Core Fertility Specialist can help you determine the correct treatment options. At Morpheus, once the diagnosis is made by Core Fertility Specialist, a counsellor explains the couple about all the treatment options available to help you make an informed decision.
Blastocyst culture: In couples who have undergone repeated failures of implantation, an alternative technique would be to culture the embryos up to the 5th day if possible, when they become blastocysts. In a natural cycle, this is the stage when the embryo actually implants in the uterus. Blastocyst culture mimics the natural cycle, thereby increasing the chances of pregnancy.
A correct diagnosis accomplished by investigations and consultation with Core Fertility Specialist can help you determine the correct treatment options. At Morpheus, once the diagnosis is made by Core Fertility Specialist, a counsellor explains the couple about all the treatment options available to help you make an informed decision.
The couple is counseled by our trained counselor to explain the medical aspects of infertility and treatment options. She helps the couple to make an informed decision and provides them moral and emotional support. The counselor assists the couple at each step of the treatment cycle. The couple's information is kept strictly confidential. Before a treatment is started, patient needs to be aware of all aspects of treatment including problems.

Psychologically, infertility is a difficult condition to deal with. During the treatment and before a pregnancy is achieved, feelings of frustration usually experienced by the infertile couple are likely to be exacerbated. Management of infertility includes emotional care of the couple.
Overall success rates for IVF have steadily improved over the last ten years. Birth rates for IVF vary according to the expertise of the centre practicing this technique.. The success rate may vary from centre to centre, since they are influenced not only by the level of expertise of the medical and embryology team but also by the characteristics of the patients treated. Patient's medical history, cause of infertility, uterine factor, systemic factor and many other conditions affect the outcome of IVF cycle.
Younger age group, normal uterus, absence of endometriosis, infection or Tuberculosis are the factors indicative of more successful outcome of fertility treatment.

In any type of infertility treatment, important factors need to be taken into account when referring to success rates. The age of the woman and the duration of the couple's infertility are likely to influence the success of treatment. In women, fecundity decreases as age increases, particularly after 37 years of age. When the woman is being treated, her chances of conceiving can be lessened if her partner also has infertility problems (e.g. poor quality sperm).
The expected success rate from IVF cycle is in the range of 30 to 35 %.

Though every clinic aims to succeed in helping every couple that hopes to conceive, in reality, this cannot be guaranteed. In our practice, we work with the couple to explore the causes of infertility and to outline all possible treatment options. The success rate may vary from centre to centre, since they are influenced not only by the level of expertise of the medical and embryology team but also by the characteristics of the patients treated. Patients' medical history, cause of infertility, uterine factor, systemic factor and many other conditions affect the outcome of IVF cycle.
It takes approximately six to eight weeks for each complete IVF or ICSI cycle. For first 10-15 days, the ovary of the woman is down regulated. This is followed by injection of hormones (FSH) for 7-12 days to stimulate the ovaries for developing multiple eggs. Ovum pickup is done and the retrieved ovum (egg) is injected with the sperm under high power microscope. This is called ICSI. The fertilized egg is then cultured for 2 days inside an incubator under optimal conditions. The embryo thus formed is transferred inside the uterus (womb) for implantation. Test to detect pregnancy is done 14 days after Embryo Transfer.
The time around the ovulation is most fertile. Having unprotected intercourse during this period leads to pregnancy. Ovulation is release of a mature egg from the ovary and it takes place 14 days prior to the start of next menstruation (bleeding). Usually the fertile period is one week before and after the probable date of ovulation.
This is mostly due to sexually transmitted diseases (for example Chlamydia or gonorrhoea) or complicated appendicitis, Tuberculosis or Pelvic Inflammatory Disease (PID) can also cause damaged tubes. Other causes are multiple miscarriage, abdominal operations (gynaecological operations, caesarean section, sterilisation or other) and diseases like Crohn's disease. Affected patients can have fertility problems and are at risk for having a pregnancy located in the tubes (ectopic or tubal pregnancy).
Endometriosis refers to presence of endometrium (the inner lining of the uterine wall) outside the uterine cavity, in the pelvis, ovaries etc. It is one of the most complex and scientists are still trying to understand its cause and its relationship with infertility. Although endometriosis has been considered a pathological or separate disease entity, it may not be a disease at all. It may actually be the clinical manifestation of a more basic underlying disorder, such as a basic chemical or physiological abnormality that affects the tubal motility or immune system which could be responsible for the initiation or progression of endometriosis in patients with retrograde menstrual flow.
PCOS affects about 4-6% of all women. It is essentially an ovulation disorder. Several factors contribute to the disease. Presently scientists believe that PCOS is a genetic disorder. The major features of this syndrome are irregular or no menstruation, hirsutism and acne due to high levels of male hormones(testosterone), obesity (40-50%), high insulin levels with risk for developing diabetes and large cystic ovaries can be detected on ultrasound. Women with PCOS usually present with infertility. The treatment possibilities are mostly focused on ovulation induction to ensure that a monofollicular growth occurs and ovulation takes place. For this, several drugs are used (clomiphene citrate, bromocriptine, gonadotrophins) and weight loss is strongly advised.
Anatomical abnormalities of uterus and damaged Fallopian tubes can be corrected by Advanced Reproductive Surgeries. Advanced reproductive surgery involves meticulous surgical technique for optimal results. Reproductive Surgeons treat tubal obstruction, endometriosis, uterine fibroids, scarring of the ovaries or other pelvic structures resulting from pelvic inflammatory disease (PID) in the female.
No. It is required for those patients where medical history suggests PCOD (Polycystic Ovarian Disorder), adhesions, endometriosis, blocked Fallopian tubes.

The laparoscope allows visual inspection of the pelvic organs through a very tiny incision. Abnormalities that lead to infertility can be treated surgically by removing scar tissue, laser, coagulate, or excising endometriosis, and repairing tubes blocked at the Fimbrial end. Many types of minor female reproductive surgery can be performed laparoscopically as day care surgery.
Cryopreservation means preserving in a frozen condition.

Embryo Cryopreservation is freezing of embryos in liquid nitrogen at temperature of -196oC. It is used for preservation of surplus good quality embryos which can be used for subsequent cycles. The process is carried out by highly skilled and trained embryologists, following international standards to ensure minimal damage to embryos.
Painful periods do not affect fertility. In fact, for most patients, regular painful periods usually signal ovulatory cycles. However, progressively worsening pain during periods (especially when this is accompanied by pain during intercourse) may mean you have endometriosis which in turn may affect your fertility.
As long as the periods are regular, this means ovulation is occurring. Some normal women have menstrual cycle lengths of as long as 40 days. Of course, since they have fewer cycles every year, the number of times they are "fertile" in a year is decreased. Also, they need to monitor their fertile period more closely, since this is delayed (as compared to women with a 30 day cycle).
Sperms are ejaculated with the seminal fluid. During Assisted Reproductive Technique (IUI or IVF or ICSI), the sperms are extracted from the semen by a series of processes such as
  • centrifugation and washing to select the active sperms and leave the immotile or dead sperms behind or
  • selection of best sperm by making them swim through a denser medium
These lab procedures are referred as sperm preparation or sperm washing.
Along with their intended benefits, drugs used to treat infertility may on occasion cause side effects. In ovulation induction, close monitoring of follicular growth is crucial to ensure successful treatment. Monitoring techniques (such as ultrasound scan and blood tests) and adequate use of treatment protocols help the physician to avoid Ovarian Hyperstimulation Syndrome (OHSS) and minimize the risk of multiple pregnancies. Current treatment protocols have been designed in a way to reduce the risk of multiple births and OHSS though they are not completely avoidable.
Common local side effects experienced by patients who receive Gonadotropins by intramuscular injection include skin redness, swelling and bruising. Pain and discomfort sometimes reported after intramuscular injections are now likely to be lessened with the availability of Gonadotropins produced by recombinant DNA - or genetic engineering - techniques which are administered by subcutaneous injection. Water retention may lead to weight gain in some patients
Multiple births occur more frequently after infertility treatment than in the normal population. About 80% of pregnancies achieved following simple ovulation induction with gonadotrophins result in single births, the remaining 20% being multiple pregnancies, mostly twin pregnancies. New treatment regimens carefully adapted to the patient's response help to decrease the risk of a multiple pregnancy. After IVF, one pregnancy out of four is multiple (20% twin pregnancies and 3-4% triplets. In IVF centres, physicians now frequently choose to place a maximum of two embryos inside the uterus, to further reduce the chance of multiple births.
Egg donor program is offered to women with Premature Ovarian Failure or those with poor quality eggs. In such a case, an egg donor is chosen who donates her eggs which are fertilized with the sperm of the husband. The selection of a donor is done by the centre and anonymity of the donor as well as the patient is strictly maintained.

This program is advised to a couple where
  • Wife's ovaries are unable to produce good sufficient eggs (Poor Ovarian Reserve)
  • Premature Menopause (Premature Ovarian Failure)
  • Wife's eggs are of poor quality
  • Ovaries have been removed or destroyed as a result of previous disease or surgery.
A male partner may have difficulty in ejaculating due to psychological or medical reasons. Surgical Sperm Retrieval is offered to couple with Azoospermia (no sperm in the semen).
  • PESA (Percutaneous Epididymal Sperm Aspiration) is done in case of blocked ducts leading to azoospermia. Here, under local anesthesia, a needle is inserted in the duct and the sperms aspirated.
  • TESE (Testicular Sperm Extraction) is done in case of non-obstructive Azoospermia. Under local/short general anesthesia, sperms are obtained by biopsy from testes directly.
  • TESA (Testicular Sperm Aspiration) is done in case of non-obstructive Azoospermia. Under local/short general anesthesia, sperms are obtained from the testes by relatively less invasive procedure.
  • MESA (Microsurgical Epididymal Sperm Aspiration): refers to the process of microscopic surgery used to retrieve the sperms from the ducts that convey them from the testicles. This is attempted in case there's an obstruction to the duct (obstructive Azoospermia).
TESE or MESA is a technique developed for patients with no sperm cells in their sperm due to an undeveloped or obstructed spermatic cord. The cause of obstruction can be a former sterilisation or an infection of the epididymis. When the testicles make no sperm cells at all, of course TESE or MESA is not possible.

The sperms thus retrieved are used for ICSI.
Sperm donor program is advised to a couple where husband's semen has no sperm. For the couples opting for donor sperms, we procure semen sample from certified sperm banks. Donor IUI or IVF/ICSI is offered as per indication. The confidentiality and anonymity of the sperm donor as well as recipient couple is strictly maintained.
Surrogacy program is advised in cases where the woman is unable to carry the pregnancy. The eggs are retrieved from the biological mother and fertilized with the sperm of biological father. The embryos thus formed are transferred inside the uterus of the surrogate who carries the pregnancy for the commissioning couple till the birth of the child.

A legal contract is signed between the surrogate mother and biological parents to facilitate this program

This program is advised to a couple where
  • Wife has absent or malformed uterus congenitally
  • Uterus have been removed surgically
  • Wife is unable to carry the pregnancy due to predisposed medical conditions like heart disease
  • Repeated implantation failures or miscarriages despite good quality embryos